Best Stem Cell Banking Clinics in Whitefield | Bangalore
Best Stem Cell Banking Clinics in Whitefield. Sunshine Dental clinic provides Best Stem Cell Banking Treatment in whitefield, Bangalore.
What are Stem Cells?
Stem cells are a unique type of cells that can develop into any specialized cells of an organ even after lying dormant for a long period of time. The umbilical cord is a rich source of stem cells.
Even though you have missed out on preserving stem cells during birth of your child, you can still preserve dental pulp stem cells harvested from the deciduous or milk teeth of your child.
Stem cells are a storehouse of new cells of the body. Stem cells can replace cells of any organs that have been damaged by virtue of having two unique capabilities.
There are three different types of stem cells and their sources:
- Hematopoietic Stem Cells (blood stem cells): These cells help growth of other blood cells through a process called haematopoiesis. Their source is peripheral blood and bone Bone marrow.
- Mesenchymal Stem Cells (tissue cells): These are multipotent stromal cells that can regenerate themselves into many variety of cell types. Their source is bone marrow, cord tissue and dental pulp.
Preservation of both these stem cells from the cord blood or cord tissue during the time of delivery has been possible since July 2010. For people who have been unable to take advantage of this technology or only have been able to preserve cord blood, they can still store mesenchymal stem cells from the dental pulp of the milk teeth. Within a tooth is a cavity known as pulp chamber which contains dental pulp and is considered as a storehouse of mesenchymal stem cells. A child usually has 20 milk teeth which drop off between 5-11 years of age making room for permanent teeth.
Around three to four weeks before the milk tooth is deemed to drop off, we will collect it under a planned tooth collection protocol through a painless process in order to keep the blood circulation to the cells intact and keep them healthy and useful. A pre-requisite is that teeth should be free of any cavities and oral hygiene should be.
These stem cells can be preserved for 30 years or 100 years based on the patient’s preference and cost of the procedure. It takes around two months following collection of the tooth to assess the eligibility of these cells as a number of tests have to be done before cryo-preserving according to international standards.
Advantages of Stem Cell:
- Stem cells can give a new lease of life to organs that cannot be treated by other conventional means of medical treatment.
- Diseases for which currently there is no long-term cure can be cured by stem cells.
At present stem cells are widely used for treating conditions like,
Orthopaedics: Arthritis and cartilage regeneration.
Ophthalmology: Limbal tissue regeneration
Neurology: Muscular dystrophy, Alzheimer, spinal cord injury, Parkinson disease and cerebral palsy.
AT present there are 3897 research trials going on in various stages of completion on stem cell treatment, a few in advanced stages. Certain researches have shown a great potential in the use of stem cells to treat cancers, diabetes and cardiovascular conditions.
KEY BENEFITS WITH SUNSHINE DENTAL:
Sunshine Dental employs Transcell Biologics Technology to test and store stem cells. Transcell was established in 2009 in Hyderabad by Dr. Subhadra Dravida, India’s eminent specialist in stem cell research. She obtained her doctorate from the USA and has spent over decade in stem cell research in the United States and Canada. Dr. Subhadra was one of the panelists of Dr. Yamanaka’s team from Japan, which won the Nobel Prize for stem cell research in 2012. Transcell’s state-of-the-art laboratory is designed to confirm the Mesenchymal nature of stem cells and preserve their integrity. In a survey conducted by Bioinformant, Transcell was ranked No. 4 globally and No. 1 in India for stem cell storage.
We are the only dental stem cells storage center in India, which complies with all international standards. All stem cells samples undergo a rigid viability process before they are cryo-preserved. We hold 23 patents for our stem cell process, storage and preservation technologies. Our technological expertise is spearheaded by a team of highly qualified and experienced stem cell scientists. Our inter-continental presence spans countries like Sri Lanka, Australia, Kenya, Ghana and the emirate of Dubai.
The Stem Cell Retrieval Process
Dental stem cells are extracted from teeth. The teeth are carefully chosen and extracted under a sterile environment. After removal the tooth is immediately dispatched to the Transcell laboratory under its certified doctor under the technically prescribed conditions.
We are the only dental stem cell bank in India that meticulously follows all pre-preservation investigation protocols. A tooth extracted by Sunshine Dental undergoes the following process in Transcell’s laboratory before its stem cells are qualified for storage.
Quality: The tooth is first checked to ensure it is free from all kinds of bacteria, virus or fungi. The tooth should also test negative for Endotoxin and Mycoplasma.
Quantity: It is imported that a sufficient amount of stem cells are removed for their multiplication. The quantity should be above the threshold limit, i.e. the stem cells should be able to proliferate easily without becoming mutative or losing their basic characteristics.
Viability: The stem cells are normally stored cryogenically at temperatures between -172 and -196 degrees centigrade. When doctors need them for any treatment, the cells are restored to room temperature (+30 degrees centigrade) in a process called ‘thawing’. While thawing, there is inevitable cell death of less than 8%. Hence the viability of the stored stem cells should be above 92%. This ensures that sufficient stem cells can resuscitate after being frozen at -196 degrees for decades.
Mesenchymal Stem Cell Characterization with Surface Markers: It is important that the stem cells preserved are mesenchymal, since mesenchymal cells have the ability to differentiate into various cell types. An important part of the overall qualification protocol is a test to establish that the cells are mesenchymal. Mesenchymal cells should test positive for surface markers CD73, CD90 and CD105 and test negative for surface markers CD34 and CD45. Mesenchymal cells are thus certified before they go on to be preserved.
Growth Properties of the Cells: The preservation protocol includes certifying the growth properties of the cells to be stored and their morphology.
After conducting such stringent tests, if the sample cells are found ineligible for storage then we take repeated samples without any additional costs to the client.